Dengue lineage nomenclature

Lineage assignment for dengue virus genomes

This page lets partner laboratories assign dengue virus sequences to the major and minor lineages using the latest global nomenclature without installing any software. Drop a FASTA file into Nextclade and within seconds you get back lineage calls, the full list of nucleotide and amino-acid mutations relative to the reference, quality-control flags, and the placement of each sequence on a curated reference tree.

Everything runs locally in your browser. Your sequences never leave your computer and are not transmitted to any server. This makes the tool suitable for unpublished data, clinical samples, and outbreak investigations where data-sharing approvals are still pending.

Choose a serotype below to launch Nextclade with the matching reference and lineage definitions pre-loaded. The "All serotypes" option runs the four-serotype Nextstrain build and is useful when serotype is unknown or for mixed batches. For very large datasets (more than a few thousand genomes), we recommend the Nextclade command-line tool, which is faster and scriptable.